According to an unexpected finding from an ongoing medical trial in the United States, a group of 12 rectal cancer patients exhibited no evidence of a tumor after using an antibody medication for six months.
No side effects after disappearing of cancer in patients
In addition to their tumors totally disappearing, none of the individuals experienced any severe side effects, according to a recent study published in the New England Journal of Medicine.
Moreover, the patients performed a set of tests, including a physical examination, endoscopy, bioscopy, PET scans, and MRI scans, but none of the results revealed a tumor.
The researchers wanted to see if an antibody medication called Dostarlimab, along with conventional chemoradiotherapy and surgery, was an effective treatment for advanced ‘deficient MisMatch Repair’ (dMMR) solid tumors.
MMR-deficient cells frequently have a lot of DNA mutations, which leads to tumors. According to the Journal, MMR insufficiency is most common in colorectal tumors, various forms of gastrointestinal tumors, and endometrial tumors.
Mismatch repair-deficient stage II or III rectal adenocarcinoma patients in the trial were administered the medicine every three weeks for six months at the Memorial Sloan Kettering Cancer Center in New York.
Meanwhile, the Simon and Eve Colin Foundation, GlaxoSmithKline, Stand Up to Cancer, Swim Across America, and the National Cancer Institute of the National Institutes of Health all contributed to the medical trial.
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